Are you curious about how long does trazodone stay in your system?
Trazodone is a medication that is commonly used to treat depression and sleep disorders.
It is important to understand how long the medication stays in your system to ensure that you are taking it properly and to avoid any potential side effects.
According to Drugs.com, after a single dose in a healthy adult, trazodone will be mostly out of your system in one to three days.
The half-life of trazodone is approximately 5 to 13 hours, which means that every 5 to 13 hours, the level in your blood will drop by 50 percent.
However, it is important to note that the exact amount of time that trazodone stays in your system can vary depending on factors such as your age, weight, and overall health.
If you are taking trazodone, it is important to follow your doctor’s instructions and take the medication as prescribed.
It is also important to avoid drinking alcohol or taking other medications that could interact with trazodone, as this could increase the risk of side effects.
By understanding how long trazodone stays in your system, you can ensure that you are taking the medication safely and effectively.

How Long Does Trazodone Stay In Your System?
If you are taking trazodone, you may wonder how long it will stay in your system.
The answer depends on various factors such as age, weight, dosage, and metabolism.
In this section, we will discuss how long trazodone can be detected in your system and what factors can affect its elimination.
According to Drugs.com, trazodone has a half-life of approximately 5 to 13 hours.
This means that every 5 to 13 hours, the level of trazodone in your blood will drop by 50 percent.
After a single dose in a healthy adult, trazodone will be mostly out of your system in one to three days.
However, the drug can be detected in the system for up to 90 days.
The duration of detection depends on the type of test administered.
For example, trazodone can be detected in a urine test for up to 4-5 days after the last dose.
On the other hand, trazodone can be detected in a hair test for up to 90 days after the last dose.
Several factors can affect how long trazodone stays in your system. These include:
- Age: Older people may metabolize trazodone more slowly than younger people.
- Weight: People with higher body weight may eliminate trazodone more quickly than people with lower body weight.
- Dosage: Higher doses of trazodone may take longer to be eliminated from the system.
- Metabolism: People with a slower metabolism may take longer to eliminate trazodone from their system than people with a faster metabolism.
In conclusion, trazodone can be detected in your system for up to 90 days, depending on the type of test administered.
The duration of detection can be affected by various factors such as age, weight, dosage, and metabolism.
If you are concerned about how long trazodone will stay in your system, it is best to consult with your healthcare provider.
Factors Influencing Trazodone’s Stay In The System
There are several factors that can influence how long trazodone stays in your system.

Some of these factors are:
Dosage
The amount of trazodone you take can affect how long it stays in your system.
Higher doses of trazodone can take longer to clear from your system than lower doses.
Age
Age can also affect how long trazodone stays in your system.
As you get older, your liver and kidneys may not work as well, which can slow down the elimination of trazodone from your body.
Metabolism
Individual differences in metabolism can also influence how long trazodone stays in your system.
People with faster metabolisms may clear trazodone from their system more quickly than those with slower metabolisms.
Other Medications
Taking other medications along with trazodone can also affect how long it stays in your system.
Some medications can slow down the elimination of trazodone from your body, while others can speed it up.
Overall Health
Your overall health can also play a role in how long trazodone stays in your system.
People with liver or kidney disease may take longer to clear trazodone from their system.
It’s important to talk to your doctor about any medications you’re taking and any health conditions you have, as they can affect how long trazodone stays in your system.
Detection Methods For Trazodone
If you are concerned about how long trazodone stays in your system, you may wonder how it is detected.

Here are some common methods used to detect trazodone in your system:
Blood Tests
A blood test is one of the most commonly used methods to detect trazodone in your system.
The medication loses 50% of its concentration in the blood every 5-13 hours.
Therefore, Desyrel metabolites can be traced in the blood for up to three days.
Urine Tests
Urine testing is another common form of drug screening used in the United States.
While trazodone is broken down in the body quickly, the metabolites produced linger in the body for longer.
Trazodone can be detected in urine for up to three days after the last dose.
Hair Tests
Hair samples can also be used to detect trazodone in your system.
Trazodone can be detected in hair for up to 90 days after the last dose.
However, hair testing is less commonly used than blood or urine testing.
Saliva Tests
Saliva testing is another method used to detect trazodone in your system.
However, it is less commonly used than blood or urine testing.
Trazodone can be detected in saliva for up to four days after the last dose.
It is important to note that the detection window for trazodone can vary depending on several factors, including the dose, frequency of use, and individual metabolism.
Additionally, certain tests can detect trazodone only after a few hours or days of taking it, while others can detect it after three months.
It is best to consult with a medical professional for more information on trazodone detection methods.
How To Flush Out Trazodone From Your System
If you have stopped taking trazodone and want to flush it out of your system, there are a few things you can do to speed up the process.
Here are some tips to help you get rid of trazodone faster:
1. Drink Plenty Of Water
Drinking lots of water is one of the simplest ways to flush out drugs from your system.
Water helps to dilute the drug in your urine and flush it out of your body faster.
Try to drink at least eight glasses of water a day to help speed up the elimination of trazodone from your system.
2. Exercise Regularly
Exercise can help to speed up your metabolism, which can help to eliminate trazodone from your system faster.
Try to exercise for at least 30 minutes a day, five days a week.
This can include activities like running, cycling, or swimming.
3. Eat A Healthy Diet
Eating a healthy diet can help to support your body’s natural detoxification processes.
Try to eat a diet that is rich in fruits, vegetables, whole grains, and lean protein.
Avoid processed foods, sugary drinks, and alcohol, as these can slow down your body’s ability to eliminate trazodone.

4. Get Enough Sleep
Getting enough sleep is important for your overall health and can also help to speed up the elimination of drugs from your system.
Try to get at least seven to eight hours of sleep a night to support your body’s natural detoxification processes.
5. Talk To Your Doctor
If you are concerned about how long trazodone is staying in your system, talk to your doctor.
They can provide you with more information about the drug and how long it is likely to stay in your system, as well as offer advice on how to speed up its elimination.
Effects Of Long-Term Trazodone Use
If you have been taking trazodone for a long time, you may be wondering about the effects it can have on your body.
While trazodone is generally considered safe for long-term use, there are some potential risks and side effects to be aware of.
One potential effect of long-term trazodone use is weight gain.
Trazodone can cause an increase in appetite, which can lead to weight gain over time.
If you are concerned about your weight while taking trazodone, it’s important to talk to your doctor about strategies for managing your appetite and maintaining a healthy weight.
Another potential effect of long-term trazodone use is the development of tolerance.
Over time, your body may become accustomed to the effects of trazodone, which can reduce its effectiveness as a sleep aid or antidepressant.
If you notice that trazodone is no longer working as well as it used to, talk to your doctor about adjusting your dosage or trying a different medication.
Long-term trazodone use can also increase your risk of developing certain side effects, such as dizziness, drowsiness, and dry mouth.
These side effects are generally mild and go away on their own, but if they persist or become severe, it’s important to talk to your doctor.
Overall, trazodone is considered a safe and effective medication for long-term use.
However, like any medication, it’s important to be aware of the potential risks and side effects and to talk to your doctor if you have any concerns.
Key Takeaways
If you are taking trazodone, you may wonder how long it stays in your system.
Here are some key takeaways to keep in mind:
- After a single dose in a healthy adult, trazodone will be mostly out of your system in one to three days.
- The half-life of trazodone is approximately 5 to 13 hours, which means that every 5 to 13 hours, the level in your blood will drop by 50 percent.
- It may take up to 6 weeks for the drug to start taking full effect. Patients are advised to carry on with the course of medication in the recommended dose even if symptoms do not ease in the first 6 weeks.
- Desyrel metabolites can be traced in the blood for up to three days.
- Trazodone is well absorbed when taken orally and peak levels occur within one hour when fasting and two hours when taken with food.
- The drug can be detected in the system for up to 90 days, but this depends on the type of test administered.
It’s important to note that the length of time trazodone stays in your system can vary depending on a number of factors, including your age, liver function, and overall health.
If you have any concerns about how long the drug may stay in your system, or if you are experiencing any side effects, be sure to talk to your doctor.